Vinpocetine Review – Top Nootropic Benefits, Safety and Dosage

Vinpocetine is a powerful natural Nootropic supplement that uniquely acts in specifically improving blood flow to the brain and known to enhance learning capacity, mood, memory, speed of recall, attention span, focus and promote healthy support to the brain.

Type: Natural Nootropic
Used For: Memory Enhancement, Brain Health, Cognitive Function, Learning Capacity, Focus, Alertness, Improving Cerebral Circulation, Age-Related Cognitive Decline, Chronic Fatigue Syndrome, Alzheimer’s Disease, Stroke
Typical Dosage: 10 mg-30 mg per day
Half-Life: 2hrs- 3hrs
Some Possible Drug Interactions: Warfarin (Coumadin), Anticoagulants, Antiplatelet Drugs
Supplement Interactions: Supplements with blood thinning effects

What is Vinpocetine ?


Vinpocetine (also known as Cavinton, Intelectol) is a unique Nootropic that has gained a positive reputation for being a safe and effective brain supplement known for its positive effects on memory, cognition and even mood.

Vinpocetine Supplement Uses & BenefitsThis supplement is considered to be a cerebral vasodilator, which means its actions cause blood vessel walls specifically in the brain to dilate, increasing blood flow to and within the brain, acting as a powerful brain booster.

This action results in improving oxygen and glucose consumption by the brain and uniquely does not change blood pressure throughout the rest of the body or add stress on the heart.

In addition, Vinpocetine acts to protect neurons from toxins and damage and boosts the production of several important neurochemicals, all leading to enhancing mental performance and promoting the optimal efficiency and health of the brain.

Vinpocetine is a semi-synthetic derivative of vincamine, the main active ingredient in the lesser Periwinkle plant, Vinca minor. In the late 1970’s, scientists at Gedeon Richter, a pharmaceutical company in Eastern Europe isolated Vinpocetine, one of 30 alkaloids extracted from the Periwinkle plant and one which is considered to be the most significantly responsible for its cognitive benefits.

Isolating this compound in a lab from other alkaloids found in vincamine allowed for greater purity of the extract and a higher safety profile. Since than, Vinpocetine has been mass produced as a prescription drug used throughout Europe and Japan in the treatment of cerebrovascular disorders and age-related memory impairments. It is also being investigated for its potential use in the treatment of Alzheimer’s disease and Parkinson’s disease.

In the United States and other countries, Vinpocetine is sold as a dietary supplement and is popularly used as a Nootropic tool to reduce brain fog, mental fatigue, enhance memory function and boost cognitive performance. It is also promoted as one of the best anti-aging supplements.

This article will discuss how Vinpocetine works to positively affect brainpower, some of the other uses of Vinpocetine and its related potential side effects so you can determine whether this supplement is right for you.

Vinpocetine Benefits For Brainpower and Cognition


Almost all the primary noted benefits of Vinpocetine are related to its proven effect as a cerebral vasodilator, improving and increasing blood flow to the brain and acting as an anti-inflammatory.

These actions are believed to be at the center of this supplements positive effects on overall cognitive performance and memory enhancement.

Vinpocetine slightly relaxes or dilates blood vessels in the brain, uniquely targeting the cerebrum, the part of the brain involved in decisions, emotions, thoughts and almost everything we do in daily life.

This results in specifically increasing blood flow to and within the brain and improves oxygen utilization without affecting blood pressure or circulation throughout the body.

Vinpocetine has also shown to target its effects on damaged brain cells and increase circulation to these areas within the brain.

Blood carries oxygen and glucose to brain cells which is than converted into ATP (adenosine triphosphate). This is the primary energy currency of neurons and other cells in the body. ATP is involved in the transportation of energy and nutrients in the brain and also acts to facilitate communication between neurons.

The brain uses more energy than any other human organ, utilizing 20% of the glucose supply coming from food consumption to fuel the millions of processes occurring in the brain daily but does not store energy. This means it needs a constant supply of fuel delivered by healthy cerebral blood flow, which is why this action is so important for mental performance and brain health.

By increasing blood flow to the brain, Vinpocetine promotes increased cerebral metabolism and helps to boost the production of ATP. When ATP availability is higher, our intellectual capacity rises (capacity to think, learn, reason, innovate, analyze etc). The presence of abundant ATP reduces feelings of mental fatigue or what is described as “brain fog” and encourages feelings of alertness and mental clarity.

Increased blood flow and circulation in the brain additionally helps to remove toxins or waste from neurons that may help to slow down the process of aging brain cells. This may be why older people are using Vinpocetine to promote enhanced learning capacity and brain plasticity.

In addition, this Nootropic compound has been observed to interact with ion channels in the brain that may boost the release of several important neurotransmitters or chemical messengers in the brain including Acetylcholine, Serotonin, Dopamine and Norepinephrine.

A greater availability of these neurochemicals can lead to enhancing memory, learning capacity, concentration, focus, lengthening attention span and may even boost mood and motivation.

Vinpocetine has been noted by many users to help enhance the ability to concentrate and focus with much more ease, thoughts are clearer, cognitive processing is much faster and recalling learned information is profoundly improved.

Finally, Vinpocetine acts as an anti-inflammatory for the brain by inhibiting cytokine, a signaling protein involved in inflammation produced by neurons. It also reduces the expression of pro-inflammatory molecules such as monocyte and vascular cell adhesion which can lead to neuronal cell death in conditions related to Alzheimer’s disease and Parkinson’s disease.

This suggests that Vinpocetine is a promising neuroprotective Nootropic substance that may help to reduce the risk of developing neurodegenerative diseases. Additionally, a reduction in inflammation may help to preserve cognitive function making this supplement a potentially powerful anti-aging tool.

According to the Natural Medicines Comprehensive Database, Vinpocetine is also used in the treatment of menopausal symptoms, chronic fatigue syndrome (CFS) and prevention of motion sickness. It is also used intravenously by medical practitioners to treat seizure disorders and stroke.



Vinpocetine Side Effects


Vinpocetine seems to be very well tolerated and is considered to be one of the safest supplements you can take. There have been no serious adverse side effects reported when using this Nootropic at the proper dosages. It is also observed to have a lower toxicity rating than caffeine.

One common side effect that you may experience is an initial feeling of being a little “vamped up”, a similar effect to drinking a weak cup of coffee but this most typically happens with higher doses and tends to go away once tolerance to Vinpocetine increases.

For this reason, it is recommended to take Vinpocetine earlier in the day to avoid the risk of difficulty falling sleeping.

In addition, some people may experience short-term, mild side effects including nausea, headache, nervousness, stomach pain or dizziness which should resolve itself within a few days. If these side effects persist, stop taking Vinpocetine and speak to your doctor for advice.

It is recommended to take Vinpocetine earlier in the day as it may cause difficulty sleeping.

Vinpocetine can affect clotting factors in the blood and platelet aggregation. Do not take Vinpocetine if you are taking blood thinners or blood thinning agents such as Tylenol or pain relievers. Avoid taking this supplement two weeks prior to a scheduled surgery or after you have undergone surgery.

There is insufficient evidence on the safety of Vinpocetine for pregnant or nursing women and children. As a precaution, avoid this supplement.

Vinpocetine Dosage Guidelines


Vinpocetine is available in 5 mg-20 mg tablets or in powder form. The recommended total daily dosage is between 10 mg-30 mg that can be divided into 2-3 doses throughout the day, taken with a meal to increase the rate of absorption.

If you are sensitive to supplements or drugs you may want to start at the lower range of the daily recommended dosage such as 5 mg, once or twice daily and only work your way up to a higher dosage once you know how your body reacts.

The effects of Vinpocetine may be dose-related. There is some evidence that suggests the effects of this supplement may be at their highest when taking 10 mg three times daily. This also suggests that taking too much of it may reduce it’s effects so it is not recommended to take more than 30 mg in total per day.

Although this supplement can be effective when taken on its own, you may want to consider stacking Vinpocetine (taking this supplement in combination) with other Nootropics such as L-Theanine or Sulbutiamine for increased benefits while preventing any potential side effects related to restlessness.

These are just dosage guidelines. It is always recommended to consult with your doctor first before taking supplements.

Vinpocetine Review


Vinpocetine is a semi-synthetic herbal brain supplement derived from the Periwinkle plant (Vinca Minor) with benefits that are quite extensive.

This Nootropic supplement is used by students to seniors to boost alertness, enhance mental clarity, reduce brain fog and improve cognitive capacities related to memory, learning, concentration and speed of recall.

It is a unique cerebral vasodilator, improving blood flow to the brain and increasing circulation which allows better absorption of nutrients and oxygen uptake. It also acts in protecting the brain from toxins and may have powerful anti-aging effects.

Vinpocetine is regarded as a highly safe supplement for healthy individuals who do not have a history of blood clotting concerns. Users online have reported positive effects on short-term memory, the speed of cognitive processing and even mood.

Some people may notice a positive difference within the first hour or day of administration while others have noticed significant effects over a few weeks of use.

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