Noopept: The Best Nootropic Supplement for Brain Power and Clarity?

Noopept

• Fast Acting Nootropic
• Supports Memory, Focus & Mood
• May Reduce Anxiety & Boost Drive
• Increases BDNF & Promotes Brain Health

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Noopept is a powerful cognitive enhancer that has grown rapidly in popularity as one of the most effective Nootropics available for improving cognition, concentration, memory, focus, logical thinking and clarity. The effects of this brain supplement work fast, making Noopept a great choice to help boost productivity just prior to mentally demanding tasks.

Type: Peptide/Cognitive Enhancer
Used For: Memory Enhancement, Focus, Cognitive Performance, Mental Energy, Brain Fog, Mood, Anxiety, Depression, Brain Health
Half-Life: 30-60 minutes
Typical Dosage: 10 mg-30 mg per day
Some Possible Drug Interactions: Cyclophosphamide
Supplement Interactions: No Known Interactions

What is Noopept?


Noopept (n-phenylacetyl-l-prolylglycine ethyl ester or GVS 111) is a powerful Nootropic compound that shares a similar mechanism of action to the popular Racetam family of Nootropics but considered more potent than Aniracetam or Piracetam, the first Nootropic ever developed. It has proven to boost some of the basic processes of your neurons which can result in enhancing several mental functions and processes.

Noopept Nootropic ReviewThis Nootropic is considered to be one of the best cognitive enhancers on the market due to its affordability and its fast-acting effects, promoting enhanced memory, learning capacity, focus, and concentration.

Noopept is even suggested to promote clearer thinking abilities, increase mental energy, enhance mood and in some user testimonials, it is said to be effective as an anxiolytic (used to reduce anxiety).

If you are not familiar with Nootropics, they are regarded as a safe class of brain supplements used to help enhance mental performance and aspects of mood that may also, in some cases, act as neuroprotectants, meaning preserving brain function and cognition.

Noopept was originally developed in the 1970’s as a means to protect the brain against oxidative damage. Since then, there has been a lot of research on this Nootropic and its demonstrated benefits.

It is currently prescribed in parts of Eastern Europe for cognitive enhancement and in a number of medical treatments and conditions.

Patented in both Russia and the USA in 1995, it was branded as Noopept by its manufacturer JSC LEKKO Pharmaceuticals. The compound gained so much popularity, it is now marketed worldwide for its Nootropic effects.

Noopept was derived from the Racetam family of smart drugs and is commonly compared to Piracetam, the first Nootropic ever developed. Although they have similar effects and actions, as well as neuroprotective properties, this compound is much more potent and bio-available due to its unique molecular structure, which is why it requires a much smaller effective dose than Piracetam or other Racetams.

Currently, in the USA, Canada, Australia, the UK and most other countries, Noopept is legal to buy, possess and use in quantities that are considered for personal use. The laws can change so it is a good idea to check the laws in your country. Although Noopept is unregulated and does not require a prescription, it is not approved by the FDA to treat or prevent any conditions.

Taken at the appropriate dosages, Noopept has no known serious adverse side effects. However, before trying Noopept, this guide can be helpful to understand how it works, examine the additional benefits, what to potentially expect when using this Nootropic and some dosage guidelines.

Noopept Benefits and Effects


Noopept’s most pointed out benefits from both users and studies indicate that this Nootropic may be effective at greatly enhancing memory, learning processes and facilitating faster recall.

This compound is thought to positively assist in the flow of signals and activity coming from the senses, which are processed by the brain and form memories.

Studies have found that it serves as a positive force for all three stages of memory including formation, consolidation and retrieval. In simple terms, this means improvements in both short-term and long-term memory and the ability to recall information much faster.

Additionally, with the use of Noopept over time, you may also notice significant improvements in the ability to absorb more information and process it with much more ease.

Noopept is also considered highly neuroprotective. This means it helps prevent damage to the brain and cell death caused by oxidative stress (i.e. excessive alcohol consumption, drugs and other factors) and in some cases, may even reverse it.

This may be beneficial in slowing down the progression of age-related cognitive decline and its further advancement in patients with cognitive impairments.

In addition, Noopept is thought to increase levels of Nerve Growth Factor (NGF) and Brain-Derived Neurotrophic Factor (BDNF) which are proteins directly related to neuroplasticity. They are involved in encouraging the growth and separation of tasks of new neurons and synapses. This may help form new neural connections that can potentially lead to improvements in all forms of cognition and is crucial for both short-term and long-term memory.

When connections and growth of new synapses are encouraged, it may improve the communication between the left and right hemispheres of the brain which has different functions in order to perform tasks. Benefits can include better verbal communication, heightened creativity, the flow of ideas and heightened logic in complex subject matters such as science and mathematics.

User reports suggest that one of the most noticeable effects of Noopept is a reduction in brain fog. This is a term to describe a lack of mental clarity, an inability to focus, poor memory recall, low attention span and lack of mental energy. While the effects of this Nootropic may not result in the same experience for everyone, for some, all these factors may improve.

Many people anecdotally report experiencing stimulating effects and feelings of much more mental clarity and an increased ability to pay attention, focus and concentrate.

Finally, there is some anecdotal evidence that suggests Noopept may have anti-anxiety effects, both for generalized and social anxiety and support levels of motivation and drive. This may be due to its potential ability to turn off or reduce activity in certain areas of the brain and stimulate others.

Although Noopept is not considered to encourage stimulant-like effects, it may have secondary stimulatory properties that may promote increased alertness, energy levels and enhanced mood by boosting blood flow to the brain which carries nutrient enriched oxygen and may help to improve the use of glucose, the brains main source of energy.

Noopept

• Fast Acting Nootropic
• Supports Memory, Focus & Mood
• May Reduce Anxiety & Boost Drive
• Increases BDNF & Promotes Brain Health


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How Does Noopept Work?


Noopept is absorbed through the gastrointestinal tract which then easily crosses the blood-brain barrier (reaches the brain) and begins to work. It reaches full concentration within 15-20 minutes due to its high bioavailability rate, which makes it one the fastest acting Nootropics other than Phenylpiracetam.

Although Noopept has been around for decades, its exact mechanisms of action is not fully understood. However, it does appear to function in a similar way to Piracetam and there are widely accepted ideas of how this supplement may work.

Once in the brain, Noopept is thought to simultaneously modulate certain receptors on brain cells that are associated with several neurotransmitters known to boost brain power, mood and cognition. These are chemical messengers that communicate information from one neuron to another.

Noopept is thought to act in boosting CPG levels, a dipeptide (cycloprolylglycine) in the brain, which indicates a build-up effect. This acts to help modulate Acetylcholine neurotransmission and AMPA glutamate receptors and their pathways.

Glutamate is a powerful neurotransmitter and the most important for normal brain function. Increasing its efficiency can improve the communication between the neurons and promote improvements in thought processes, perception and the formation of memory.

Noopept is thought to bind to Glutamatergic receptor sites and help to prevent the breakdown of this neurotransmitter which may increase its circulation in the brain and encourage more fluid movement between brain cells. This action may be where Noopept differentiates from Piracetam which is thought to have weaker effects on Glutamate.

It also thought that Noopept modulates the flow of Acetylcholine (ACh) in the brain by increasing the efficacy of these receptors and  is considered a strong cholinergic. ACh is another important neurotransmitter thought to be involved in learning, memory, focus and coordination.

Finally, trials on rats who were given Noopept over a 28 day period resulted in raising levels of Nerve Growth Factor (NGF) and Brain-Derived Neurotrophic Factor (BDNF).

These are proteins that regulate the reparation and maintenance of damaged brain cells and even encourages the growth of new brain cells, vital to long-term memory.

What Are The Experiences and Results of Noopept?


There are many user reports describing the experience and how they feel when using Noopept. It is important to keep in mind that although there are common similar effects, they can vary from person to person.

There are many Noopept testimonials and reviews online that you can find on Nootropic forums and internet communities such as Reddit that consist of experiencing a wide range of benefits. While some people attest to Noopept being the best Nootropic supplement available, others may feel that other Nootropics have worked better for them.

Experimentation may be the answer since these differences in effects can be due to lack of sleep, medications, current individual neurotransmitter levels in the brain, tolerance levels and many other factors.

With that being said, users commonly report less brain fog and more clarity when taking Noopept. Users may also notice big effects on memory. The ability to remember the smallest details with ease and even recall past events or places has been commonly reported with the use of Noopept.

Other significant experiences may be enhanced related to mental performance and brain power. You may notice that you can think faster, thoughts may seem clearer and flow better and perception may be enhanced, helping you to complete tasks with ease. You may also notice powerful effects in the ability to concentrate and focus without getting distracted.

Noopept may help some users be more socially outgoing and you may find it easier to engage in flowing, intellectual conversation. Additionally, there have been some people reporting sharper audio and visual perception. Colors are brighter and hearing is sharper.

Stacking Noopept


Noopept is considered to be one of the best Nootropic supplements available on the market. Although it can be used independently, some people commonly stack (combined use) this supplement with other Nootropics to potentially increase the effectiveness and experience a wider range of cognitive effects that other Nootropics may provide simultaneously.

If you are a beginner and considering taking Noopept, it is recommended to not stack this product with other Nootropics to start. It has a high potency and it is best to first determine how the effects of this supplement, when taken on its own, may work for you.

Common combination or stacks you may want to consider as a beginner, include taking Noopept with a high-quality choline source such as Alpha GPC or Citicoline. Noopept increases the uptake of Acetylcholine, a neurotransmitter that can produce many cognitive effects but requires choline to produce it.

For others who have already taken Noopept on its own and are considering stacking this Nootropic, common stacks reported by users include Noopept and Piracetam. These Nootropics are considered to have synergistic effects and their slight differences in the mechanisms of action may boost the overall level of enhanced cognition you may want to achieve.

In addition, Piracetam seems to work more on the formation of memory while Noopept is thought to have benefits on all three stages of memory including formation, consolidation and retrieval.

You may also want to consider stacking Noopept with any herbal or natural Nootropic to achieve desired effects.

Does Noopept Have Side Effects?


Although Noopept has many positive and powerful scientific and anecdotally reviews, it appears to have few reported side effects or risks of dependency despite its potency. At the recommended dosages, studies seem to attest to its safety.

Potential side effects are rare but if taken outside the recommended dosage, side effects can include dizziness, fatigue, nausea, restlessness and problems sleeping.

Irritability is the most common reported side effect of Noopept when taken consecutively for a long period of time. It is recommended to cycle this Nootropic if this occurs to allow your body to readjust.

Also, caution is advised when taking Noopept with other stimulants such as amphetamines. Evidence suggests that it may enhance their effects

In addition, if you are pregnant or nursing, this supplement should be avoided for precautionary purposes.

Noopept Dosage Guidelines


How much Noopept should you take? Noopept is very bio-available and potent so a small amount is sufficient. The recommended dosage is between 10 mg-30 mg per day.

For optimal effects, the suggested dosage is 10 mg taken twice a day, once in the morning and once in the afternoon. However, it is recommended to start at 5 mg-10 mg once daily and only increase the dosage once you are certain of the effects. Do not exceed 30 mg per day.

Noopept is suggested to be administered in small doses, several times a day to help maintain an effective level in the system due to it’s short but potent half-life. For faster absorption, you can place Noopept under your tongue (sublingual administration).

Noopept is sold in powder, tablet and capsule form. It is considered semi-water soluble, so it may sink to the bottom of the glass when taken in powder form with water or juice. A better option may be capsules or tablets.



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