Galantamine Review for Memory, Cognition & Lucid Dreaming

Galantamine is a powerful diverse supplement, well known for its Nootropic properties leading to enhanced brain power, memory and focus with additional benefits promoting improved sleep quality and inducing lucid dreaming.

Type: Acetylcholinesterase Inhibitor/Natural Nootropic
Used For: Memory, Learning Capacity, Attention, Focus, Alertness, Age-Related Cognitive Decline, Lucid Dreaming, Alzheimer’s disease, Myasthenia Gravis
Half-Life: 7hrs
Typical Dosage: 4 mg-24 mg per day
Some Possible Drug Interactions: Acetaminophen, Bupropion,
Lohexol, Lopamidol, Metrizamide, Naltrexone, Tramadol
Supplement Interactions: No known interactions

What is Galantamine?


Galantamine is a Nootropic supplement derived from the bulbs of the flowers in the Galanthus Causasius plant (snowdrops), certain daffodils (snowflake) and red spider lilies.

Galantamine Benefits & UsesIt is an alkaloid substance which is part of a group of naturally occurring organic chemical compounds that are produced from several types of organisms such as plants and fungi. It can also be synthetically produced with a formulation that was originally developed in the early 1960’s.

As a Nootropic supplement, it is most popularly used to enhance several aspects of mental performance such as memory, learning capacity, mental processing, reasoning and creative thought.

Additionally, Galantamine has been reported to promote relaxation after a stressful day and is even used by many individuals to encourage longer states of REM sleep to achieve lucid dreaming, which is based on a state of awareness while dreaming.

Galantamine is marketed under several brand names including Razadyne, Reminyl ER, Nivalin and Lycoremine. Galantamine (hydrobromide) has several clinical uses. In Europe, it has been used to treat conditions including myasthenia, myopathy and sensory/motor dysfunctions associated with central nervous system disorders.

In the United States, it is an FDA approved drug for use in the treatment of mild to moderate Alzheimer’s disease, where it is believed to restore the balance of certain natural chemicals in the brain that may help memory and daily mental functioning in these patients.

Let’s review what the potential benefits and uses are of Galantamine supplements, how they work, some of the reported results when using this supplement as a Nootropic and the safety and dosage guidelines.

Benefits and Uses of Galantamine


The main effect of Galantamine is to increase the levels of circulating Acetylcholine in the brain. This an important neurotransmitter that is thought to play a crucial role in memory, attention and learning. This action may be responsible for the many uses and potential Nootropic benefits of this supplement.

The primary clinical use of Galantamine in the USA is as an FDA approved, adjunct treatment for Alzheimer’s, where it is available both over the counter and as a prescription medication to help improve memory, mental performance and confusion, symptoms associated with this disease.

Additionally, Galantamine is popularly used as a Nootropic supplement by healthy individuals noted to have positive effects on several cognitive functions including improving memory recall, concentration, learning capacity, mental acuity, the speed of cognition and may even produce mood-boosting effects.

Galantamine seems to have additional benefits relating to improving the quality of sleep. Users who take this supplement later in the day have experienced the ability to fall asleep with more ease and user reviews indicate that it promotes deeper sleep states (REM) where users wake up feeling refreshed and more rested.

In addition, Galantamine has been found to increase dream activity and even dream clarity which may be due to elevated Acetylcholine levels in the brain. This supplement has been reportedly used to achieve lucid dreaming states, where an individual is aware that they are dreaming and can control scenarios and outcomes that happen within the dream.

Finally, Acetylcholine is thought to help maintain attention by heightening sensory perception while we are awake. Increased circulation of this neurotransmitter may result in colors and sounds becoming sharper.

Effects of Galantamine in the Body and Brain


Galantamine is known to hinder an enzyme called Acetylcholinesterase (AchE) from breaking down Acetylcholine, an important natural signaling chemical in the brain that is thought to be involved in memory formation, attention and cognition.

In turn, this action increases the circulation of Acetylcholine, raising its level and duration of action within the brain. Increased levels of this important neurotransmitter can result in boosting brain function and several cognitive processes such as memory, learning, higher reasoning and sustained attention can be enhanced.

This action is similar to Huperzine A, which is another acetylcholinesterase inhibitor and popularly used to achieve similar effects.

As we age, natural Acetylcholine levels decline and low levels of this neurotransmitter have been specially indicated in individuals suffering from Alzheimer’s disease and other forms of cognitive impairments in older individuals.

Another suggested mechanism of action of Galantamine is the modulation of presynaptic nicotinic receptors which encourages favored release of Acetylcholine and other important chemicals in the brain involved in memory functions.

Additionally, Acetylcholine plays important roles in the signaling of muscle movement, sensation of pain, regulation of the endocrine system and REM sleep functions. Galantamine (hydrobromide) is used clinically in Europe for several conditions such as myopathy which results in muscular weakness.

Low levels of Acetylcholine can hinder the ability of this chemical to send signals to other nerve cells which may lead to other medical conditions and complications such as myasthenia gravis.

Is Galantamine Safe to Use?


The use of Galantamine typically has very few associated side effects if any at all in healthy adults. It is considered a safe and well-tolerated supplement within the appropriate dosages.

Although cases are rare, allergic reactions to this supplement can occur due to flower allergies, especially to daffodils. If you experience an allergic reaction developing including rash, itching, swelling of the mouth or face and/or trouble breathing, discontinue use of this supplement immediately and seek medical attention.

Other potential side effects of Galantamine include diarrhea, dizziness, nausea, loss of appetite and fatigue. Do not take Galantamine in combination with Huperzine A which is another acetylcholinesterase inhibitor.

It is always recommended to speak with your doctor first before taking new supplements, especially if you have any previously diagnosed conditions or taking medications to ensure that this supplement is right for you.

Galantamine Dosage Guidelines


Galantamine is a potent supplement that only requires a small dosage to achieve effects. The typical dosage range is between 4 mg-16 mg in total per day, which at the higher range, can be divided into two administrations daily for healthy people looking to achieve Nootropic or lucid dreaming effects.

This supplements half-life is approximately 7 hrs. It is recommended to start at the lower daily range (4 mg once per day) first for a few days to determine an effective and sufficient dosage that may work best for you before raising the dosage.

In clinical trials for Alzheimer’s patients, daily dosages of up to 32 mg have been used with significant effects reported at dosages ranging between 16 mg-32 mg daily. However, it is still recommended to initially start at the lowest dose of 4 mg per day to first determine how this supplement affects you before increasing the dose.

Galantamine can also be safely stacked with cholinergic supplements to increase the effects of acetylcholine such as Alpha GPC or CDP Choline. This supplement is also commonly stacked with several Racetam Nootropics including Aniracetam or Piracetam, which are also thought to aid in raising the release of Acetylcholine.

These are just guidelines. If you have any concerns or questions, speak to your doctor first.

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