Oxiracetam Nootropic Review-Effects on Memory, Learning & Thinking

Oxiracetam

• Boosts Focus & Alertness
• Promotes Analytical Thinking & Memory Enhancement
• Heightens Energy Level

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Oxiracetam is considered a safe and powerful Nootropic supplement. Considered to be a pure cognitive enhancer and mild stimulant, it is widely used to promote improvements in many cognitive processes including concentration, cognitive speed, memory recall, learning capacity, focus, logical thinking and mental energy.

Type: Racetam Nootropic
Used For: Memory Enhancement, Concentration, Learning Capacity, Enhanced Analytical Thinking, Mental Performance, Mental Energy, Cognitive Decline, Dementia
Half-Life: 7hrs-8hrs
Typical Dosage: 750mg-2,400mg per day
Some Possible Drug Interactions: Amphetamines, Nicotine, Carbamazepine
Supplement Interactions: No known Interactions

What is Oxiracetam?


Oxiracetam is one of the most popular and highly regarded Nootropics, noted to have impressive cognitive enhancing properties and mild stimulant-like effects that promote feelings of increased motivation, mental energy and alertness. It is considered a safe and effective true cognitive enhancer that may even contribute to brain health and help fight against the aging process of the brain.

It continues to be a favorite among Nootropic users for its noted benefits on enhancing several cognitive processes, such as memory formation and retention, learning capacity, logical thinking and the ability to focus.

Oxiracetam Benefits & EffectsOxiracetam is the third member of the Racetam class of Nootropics and synthesized in the 1970’s. It’s first published study dates back to the early part of the 1990’s.

Since then, numerous studies have been conducted on its cognitive properties and promising potential clinical uses in the treatment of many cognitive related neurological conditions including ADHD, autism and Alzheimer’s disease. However, there is limited research at this time to support its effectiveness for these uses.

While Oxiracetam has not been used clinically as broadly as other Nootropics, it has been used in some countries under the brand names Neuromed and Neuracetam with its most common use as a cognitive enhancer.

This smart drug is a derivative of Piracetam, the first Nootropic ever synthesized with an added hydroxyl group to its chemical structure and considered to be five times more potent.

If you are not familiar with these types of brain-boosting Nootropics, Racetams (Aniracetam, Oxiracetam, Piracetam, Phenylpiracetam, Coluracetam, Pramiracetam and others) share a similar chemical structure working to help in slightly adjusting the actions of certain neurotransmitters that are linked to important cognitive processes. They are known to improve memory, learning capacity, focus, energy levels and mood, additionally offering positive effects on the basic components of brain health.

In the United States, Oxiracetam is not approved by the FDA to prevent or treat any conditions or to be used for any medical uses. It is currently widely available to purchase online and used to promote enhanced cognitive function.

If you are considering trying Oxiracetam, it is important to first understand what the associated benefits are of this powerful brain booster, how it works, potential side effects and dosage guidelines.

Oxiracetam Benefits For Memory and Learning


The main benefits associated with Oxiracetam are related to substantially enhancing several mental functions to boost fluid intelligence (logic and problem solving), overall learning capacity, reasoning, attention span, focus and memory in healthy individuals.

In addition, this Nootropic agent is thought to act as a mild stimulant, increasing mental energy, alertness and motivation, which is an effect described by many user reports as a calm and effective energy boost without the nervousness that may accompany the use of general stimulants.

This compound has been observed to modulate Acetylcholine and Glutamate receptors in the brain, which may increase and even restore their levels, to positively enhance cognitive functioning.

These are two powerful neurotransmitters thought to be involved in learning capacity, focus, encoding new memories, concentration, reasoning, attention span, perception and promoting neuroplasticity (forming new neural connections) that encourage long-term memories to form.

This Nootropic agent has been observed in countless studies to enhance both short-term and long-term memory performance. When using this supplement you may notice improvements in the ability to retain information and recall it with greater speed.

There has been a significant amount of users reporting the positive effects of this Nootropic on memory, noting they can remember facts, conversations, creative ideas, figures, both from processed short-term information and memories from long ago, with a more fluid thought process.

This makes this Nootropic ideal as a study aid, a tool for work or for individuals looking to improve both their learning capacity and attention span. Oxiracetam is indicated by many users to enhance the speed and ease of recalling new information and to heighten the ability to focus for long periods of time without mental fog even when the effects are wearing off.

In addition, Oxiracetam is particularly known to help improve spatial and contextual learning capacities, that may help you make sense of newly learned information by boosting thinking skills and encouraging faster connections drawn from previous memories, experiences and locations.

Furthermore, clinical studies have shown that Oxiracetam increases blood flow to the brain, which carries oxygen and glucose, the brains main energy source. This is a very important factor for overall cognitive capacities and may promote faster-thinking processes and greater mental stamina throughout the day.

Additionally, Oxiracetam is implicated to have neuroprotective properties and positive effects on overall brain health by protecting and potentiating reversal of damage to brain cells that may have been due to factors such as alcohol consumption.

Finally, studies have shown that this compound may act as a type of anti-oxidant, helping the brain excrete toxins that may contribute to positively protecting long-term neurological processes.  In other words, it may act to slow down age-related cognitive decline.

Oxiracetam

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• Heightens Energy Level

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Oxiracetam Effects on Logical and Technical Thinking


One of the major purported benefits of Oxiracetam is the enhancement in logical and technical thinking abilities, as well as spatial reasoning skills. This may be why it is indicated to be the most favored Nootropic among engineering and science students.

Researchers believe that Oxiracetam enhances the functions of the left side of the brain as the result of the modulation of several neurotransmitters. It was reported from these studies that Oxiracetam promotes beneficial effects on problem-solving skills, logical thinking, spatial reasoning and attention.

The left side of the brain is indicated to control these cognitive processes, in addition to technical and analytic thinking, writing skills, language, sensory perception, mathematically and scientific skills.

Oxiracetam may help users analyze technical material with more ease, improve verbal fluidity, enhance the ability to problem solve and to reach decisive answers.

Users report experiencing substantial effects on the ability to think faster and process information logically, although for some people, these effects may be subtle or increase over time with continued use.

Finally, the effects of this supplement on sensory perception has been widely reported by users, particularly in enhancing visual and auditory perception. The effects are described as “seeing and hearing the world differently” where colors are more vibrant and sounds are deeper.

How Oxiracetam Works


The exact mechanisms of action of Oxiracetam is still not fully understood. However, researchers do believe that the positive effects of this supplement on cognitive functions are due to influencing the release of two powerful brain chemicals, Acetylcholine and Glutamate which are thought to play vital roles in memory formation and retention, learning and general cognitive function.

Oxiracetam is water-soluble and absorbed through the intestinal tract, reaching peak blood concentration within approximately an hour of ingestion. It is then thought to easily cross the blood-brain barrier and affect the cholinergic and glutamatergic systems.

It is believed to affect cholinergic receptors in the brain in order to increase the level of Acetylcholine (ACh). By inhibiting the desensitization of these receptor sites, or cells that respond to ACh throughout the brain, they may be more effective at sending signals to the hippocampus, an area of the brain linked to memory and learning behavior.

This is a similar action to other members of the Racetam family of Nootropics but Oxiracetam effects are regarded as more potent than Piracetam, does not have the additional mood-enhancing effects of Aniracetam and is considered a stronger focus enhancer than Pramiracetam.

In addition, Oxiracetam falls into the class of Ampakine Nootropics which may be due to modulating glutamatergic AMPA receptors in the brain that are involved in promoting fast synaptic transmission, synaptic plasticity, learning capacity and memory.

Ampakines tend to have a mild stimulant effect without the associated side effects of other stimulants such as Ritalin or amphetamines.

Oxiracetam may increase the release of Acetylcholine in the brain. This neurotransmitter requires choline to produce it and may cause headaches, agitation, fatigue and mental fog if there is a potential deficit of this nutrient.

To ensure there is enough of this nutrient to supply the brains demand for Acetylcholine, it is highly suggested to stack Oxiracetam with a source of choline.

There a few good sources of choline available which are also purported to offer cognitive effects to stack with Oxiracetam including Alpha GPCCiticoline (CDP-Choline) or Centrophenoxine.

Commonly, Oxiracetam is stacked with many other cognitive enhancers, smart drugs or natural brain supplements (especially with other Racetams) to enhance the effects or for synergistic effects that other supplements may offer.



Oxiracetam Side Effects


Oxiracetam is considered to be a safe, extremely well tolerated and non-toxic cognitive enhancer when taken at the appropriate dosages. There has not been any serious side effects reported with the use of this supplement and side effects are more likely to occur at high dosages.

There have been reports of nausea, dizziness and gastric distress, mostly from users who take high doses of Oxiracetam. Lowering the dosage will often alleviate these side effects. If you are experiencing these side effects at the proper dosage, discontinue using this Nootropic.

In rare cases, some users have reported anxiousness and insomnia while using Oxiracetam which may be due to its known, mild stimulant properties. These effects can be stronger for some people than others. If you experience disruptions in your sleeping patterns, it is suggested to try taking Oxiracetam earlier in the day.

The most common reported side effect of Oxiracetam are headaches which is a similar side effect to all Racetam Nootropics. Stacking Oxiracetam with a source of choline can often remedy this problem.

There is not enough research on the safety of this supplement for pregnant or nursing women and therefore should be avoided.

There is no information available on how Oxiracetam may affect people with medical conditions. It is always advised to speak with your doctor or health care professional first before using supplements.

Dosage Guidelines and How to Use Oxiracetam


Oxiracetam is believed to be a powerful cognitive enhancer that is considered safe to use. Nevertheless, it is a potent Nootropic agent and following dosage guidelines for proper usage is important to avoid the potential risk of unwanted side effects.

The typical daily dosage ranges from 750 mg up to 2,400 mg which can be taken once or divided up into two to three administrations throughout the day.

It is recommended to always stay within the lower dosage range when starting on any new Nootropic supplement and only increase the dosage once you have determined your body’s effect in order to find what may work best for you.

Oxiracetam is known to have mild stimulant properties and has an approximate half-life of 8 hours. It is best to take earlier in the day to avoid potential problems falling asleep. Additionally, this means it may only be necessary to take it once per day.

It has not shown to have any additional effects at higher dosages than the daily range. However, sources have advocated starting with “attack doses” to initiate faster effects that can be typically two to five times higher than the recommended dosage.

People can respond to Nootropics differently. This practice may result in unwanted side effects due to this supplements known mild stimulant properties and this approach is highly inadvisable.

Oxiracetam is water-soluble so it does not need to necessarily be taken with food.

Although studies have not confirmed tolerance to this drug, there have been some users who report that they have built up a tolerance to the effects of Oxiracetam after continued use. Instead of raising the dosage, it is recommended to cycle off this Nootropic for awhile to regain its efficacy. You may want to consider cycling Oxiracetam with other Racetams.

Oxiracetam may increase the release of Acetylcholine in the brain. This neurotransmitter requires choline to produce it and may cause headaches, agitation, fatigue and mental fog if there is a potential deficit of this nutrient.

To ensure there is enough of this nutrient to supply the brains demand for Acetylcholine, it is highly suggested to stack Oxiracetam with a source of choline. A few good sources available you may want to consider include Alpha GPCCiticoline (CDP-Choline) or Centrophenoxine.

Commonly, Oxiracetam is stacked with many other cognitive enhancers, smart drugs or natural brain supplements (especially with other Racetams) to enhance the effects or for synergistic effects that other supplements may offer.

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